Microbial Pathogenesis of Community-Acquired MRSA Infections

Higher incidence of perineal community acquired MRSA infections among toddlers

BACKGROUND A six-fold increase in pediatric MRSA infections, prompted us to examine the clinical profile of children with MRSA infections seen at Mercy Children's Hospital, Toledo, Ohio and to characterize the responsible strains. METHODS Records were reviewed of pediatric patients who cultured positive for MRSA from June 1 to December 31, 2007. Strain typing by pulsed field gel electrophores...

Community-acquired MRSA: a practitioner's guide.

Community-Acquired MRSA: A Burgeoning New Epidemic

Methicillin-Resistant Staphylococcus aureus (MRSA) has been a recognized pathogen for almost half a century. Until recently, MRSA was confined predominately to hospitals, nursing homes, and other healthcare facilities that care for debilitated and chronically ill patients (Healthcare-Associated, or HAMRSA). In the last decade, however, MRSA has caused rapidly increasing numbers of invasive infe...

Author's response to reviews Title: Higher Incidence of Perineal Community Acquired MRSA Infections among Toddlers Authors:

An Outbreak of Severe Infections with Community-Acquired MRSA Carrying the Panton-Valentine Leukocidin Following Vaccination

BACKGROUND Infections with community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) are emerging worldwide. We investigated an outbreak of severe CA-MRSA infections in children following out-patient vaccination. METHODS AND FINDINGS We carried out a field investigation after adverse events following immunization (AEFI) were reported. We reviewed the clinical data from all case...